Israeli scientists: ‘In a few weeks, we will have coronavirus vaccine’

Home Forums Main Forum Israeli scientists: ‘In a few weeks, we will have coronavirus vaccine’

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    • #11158

      Once the vaccine is developed, it will take at least 90 days to complete the regulatory process and potentially more to enter the marketplace.

      Israeli scientists are on the cusp of developing the first vaccine against the novel coronavirus, according to Science and Technology Minister Ofir Akunis. If all goes as planned, the vaccine could be ready within a few weeks and available in 90 days, according to a release.

      “Congratulations to MIGAL [The Galilee Research Institute] on this exciting breakthrough,” Akunis said. “I am confident there will be further rapid progress, enabling us to provide a needed response to the grave global COVID-19 threat,” Akunis said, referring to the disease caused by the novel coronavirus.
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      For the past four years, a team of MIGAL scientists has been developing a vaccine against infectious bronchitis virus (IBV), which causes a bronchial disease affecting poultry. The effectiveness of the vaccine has been proven in preclinical trials carried out at the Veterinary Institute.

      MIGAL is located in the Galilee.

      “Our basic concept was to develop the technology and not specifically a vaccine for this kind or that kind of virus,” said Dr. Chen Katz, MIGAL’s biotechnology group leader. “The scientific framework for the vaccine is based on a new protein expression vector, which forms and secretes a chimeric soluble protein that delivers the viral antigen into mucosal tissues by self-activated endocytosis, causing the body to form antibodies against the virus.”

      Endocytosis is a cellular process in which substances are brought into a cell by surrounding the material with cell membrane, forming a vesicle containing the ingested material.

      In preclinical trials, the team demonstrated that the oral vaccination induces high levels of specific anti-IBV antibodies, Katz said.

      “Let’s call it pure luck,” he said. “We decided to choose coronavirus as a model for our system just as a proof of concept for our technology.”

      avirus causing the current worldwide outbreak, the MIGAL researchers examined it and found that the poultry coronavirus has high genetic similarity to the human one, and that it uses the same infection mechanism, which increases the likelihood of achieving an effective human vaccine in a very short period of time, Katz said.

      “All we need to do is adjust the system to the new sequence,” he said. “We are in the middle of this process, and hopefully in a few weeks we will have the vaccine in our hands. Yes, in a few weeks, if it all works, we would have a vaccine to prevent coronavirus.”

      MIGAL would be responsible for developing the new vaccine, but it would then have to go through a regulatory process, including clinical trials and large-scale production, Katz said.

      Akunis said he has instructed his ministry’s director-general to fast-track all approval processes with the goal of bringing the human vaccine to market as quickly as possible.
      “Given the urgent global need for a human coronavirus vaccine, we are doing everything we can to accelerate development,” MIGAL CEO David Zigdon said. The vaccine could “achieve safety approval in 90 days,” he said.

      It will be an oral vaccine, making it particularly accessible to the general public, Zigdon said.

      “We are currently in intensive discussions with potential partners that can help accelerate the in-human trials phase and expedite completion of final-product development and regulatory activities,” he said.

    • #11166
      David W. Roche

      Hmmm.  Will the Muslim countries take the vaccine developed in Israel?  Just wondering.

      • #11172

        What a humbling experience that would be. :whistle:

        But I can see it short lived because if  the Shiites later got sick from some other virus … it’s a given … they will readily place blame to Israel saying it came from that vaccine shot. :wacko:

    • #11173

      I read some high level leaders in Iran are infected with the virus … I wonder if we will be seeing a change in leadership that way and the crown prince (Shah’s son) being put back into place? :unsure:

    • #11209

      Per Amir’s  BeholdIsrael’s twitter

      Source Claims that the Coronavirus Death Toll in Iran Could be ‘Six Times’ Higher than Reported

      Sources from within Iranian hospitals believe that a minimum of 200 fatalities has occurred in Iran since the outbreak of CoVid-19; The US is offering help despite previous sanctions.

      Several sources from within hospital(s) inside of Iran are claiming that the death toll from the coronavirus is being highly underreported by the Iranian government. While Iran has officially reported 34 deaths after eight more were announced on Friday, the numbers compiled by individuals inside of the hospital(s) exceeds 200.

      Additionally, Iran has confirmed 143 new cases of the virus as of Friday. The majority of the fatalities have come from the capital city of Tehran as well as Qom, where the virus first came on the scene in Iran.

      Despite the economically crippling sanctions the United States has implemented on Iran, US Secretary of State Mike Pompeo announced, “We have made offers to the Islamic Republic of Iran to help. Their healthcare infrastructure is not robust and, to date, their willingness to share information about what’s really going on inside… Iran has not been robust.” Unfortunately, Iran dismissed this offer of help as nothing by a political stunt.

      Furthermore, several key Iranian officials have now contracted the virus, some of whom have been in extremely close proximity to the Iranian President Hassan Rouhani this week.

      February 29th, 2020|News

      – Fair Use –

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